| Alachua to Southern Pines (North Carolina) | 414.88 mi (667.68 km) |
| Alachua to Southfield (Michigan) | 878.45 mi (1,413.73 km) |
| Alachua to Southgate (Michigan) | 859.55 mi (1,383.31 km) |
| Alachua to Southlake (Texas) | 891.85 mi (1,435.29 km) |
| Alachua to Spanaway (Washington) | 2,434.32 mi (3,917.66 km) |
| Alachua to Spanish Fork (Utah) | 1,788.51 mi (2,878.33 km) |
| Alachua to Spanish Lake (Missouri) | 762.23 mi (1,226.70 km) |
| Alachua to Spanish Springs (Nevada) | 2,201.57 mi (3,543.08 km) |
| Alachua to Sparks (Nevada) | 2,203.41 mi (3,546.04 km) |
| Alachua to Spartanburg (South Carolina) | 358.44 mi (576.85 km) |
| Alachua to Spearfish (South Dakota) | 1,545.17 mi (2,486.71 km) |
| Alachua to Speedway (Indiana) | 724.05 mi (1,165.25 km) |
| Alachua to Spencer (Iowa) | 1,158.56 mi (1,864.52 km) |
| Alachua to Spokane (Washington) | 2,224.47 mi (3,579.95 km) |
| Alachua to Spokane Valley (Washington) | 2,215.75 mi (3,565.91 km) |
