| Appenweier to Sangeorz-Bai | 775.40 mi (1,247.89 km) |
| Appenweier to Sannicolau Mare | 615.30 mi (990.23 km) |
| Appenweier to Santana | 648.68 mi (1,043.94 km) |
| Appenweier to Satu Mare | 687.97 mi (1,107.18 km) |
| Appenweier to Scobinti | 878.27 mi (1,413.44 km) |
| Appenweier to Scornicesti | 831.68 mi (1,338.46 km) |
| Appenweier to Sebes | 751.14 mi (1,208.84 km) |
| Appenweier to Seini | 706.56 mi (1,137.09 km) |
| Appenweier to Sfantu-Gheorghe | 854.04 mi (1,374.44 km) |
| Appenweier to Sibiu | 781.38 mi (1,257.51 km) |
| Appenweier to Sighetu Marmatiei | 732.22 mi (1,178.39 km) |
| Appenweier to Sighisoara | 801.00 mi (1,289.09 km) |
| Appenweier to Simeria | 728.37 mi (1,172.20 km) |
| Appenweier to Sinaia | 855.50 mi (1,376.80 km) |
| Appenweier to Slatina | 827.58 mi (1,331.87 km) |
