| Appingedam to Sacile | 566.52 mi (911.73 km) |
| Appingedam to Sala Consilina | 981.51 mi (1,579.59 km) |
| Appingedam to Salemi | 1,107.78 mi (1,782.80 km) |
| Appingedam to Salerno | 947.61 mi (1,525.04 km) |
| Appingedam to Salo | 557.83 mi (897.74 km) |
| Appingedam to Salsomaggiore Terme | 603.94 mi (971.94 km) |
| Appingedam to Saluzzo | 599.80 mi (965.28 km) |
| Appingedam to Salzano | 586.87 mi (944.48 km) |
| Appingedam to Samarate | 538.88 mi (867.25 km) |
| Appingedam to San Benedetto del Tronto | 785.05 mi (1,263.41 km) |
| Appingedam to San Biagio di Callalta | 581.95 mi (936.56 km) |
| Appingedam to San Bonifacio | 581.70 mi (936.15 km) |
| Appingedam to San Casciano in Val di Pesa | 695.79 mi (1,119.76 km) |
| Appingedam to San Cataldo | 1,145.78 mi (1,843.95 km) |
| Appingedam to San Cesareo | 840.62 mi (1,352.84 km) |
