| Appleton to Spello | 998.11 mi (1,606.31 km) |
| Appleton to Spilamberto | 863.24 mi (1,389.25 km) |
| Appleton to Spilimbergo | 847.80 mi (1,364.40 km) |
| Appleton to Spinea | 852.44 mi (1,371.88 km) |
| Appleton to Spoleto | 1,011.08 mi (1,627.17 km) |
| Appleton to Spoltore | 1,073.87 mi (1,728.23 km) |
| Appleton to Spresiano | 841.53 mi (1,354.32 km) |
| Appleton to Squinzano | 1,311.07 mi (2,109.97 km) |
| Appleton to Statte | 1,275.36 mi (2,052.49 km) |
| Appleton to Stezzano | 761.33 mi (1,225.23 km) |
| Appleton to Strada | 923.50 mi (1,486.23 km) |
| Appleton to Stradella | 780.36 mi (1,255.86 km) |
| Appleton to Striano | 1,176.39 mi (1,893.21 km) |
| Appleton to Subiaco | 1,069.01 mi (1,720.41 km) |
| Appleton to Sulmona | 1,088.78 mi (1,752.22 km) |
