| Ascoli Piceno to Selvazzano Dentro | 196.48 mi (316.20 km) |
| Ascoli Piceno to Senago | 290.13 mi (466.93 km) |
| Ascoli Piceno to Senigallia | 62.40 mi (100.42 km) |
| Ascoli Piceno to Seravezza | 185.92 mi (299.21 km) |
| Ascoli Piceno to Seregno | 290.59 mi (467.66 km) |
| Ascoli Piceno to Seriate | 273.68 mi (440.45 km) |
| Ascoli Piceno to Sermoneta | 94.93 mi (152.77 km) |
| Ascoli Piceno to Serramanna | 338.89 mi (545.39 km) |
| Ascoli Piceno to Serravalle Pistoiese | 155.99 mi (251.05 km) |
| Ascoli Piceno to Sessa Aurunca | 113.14 mi (182.08 km) |
| Ascoli Piceno to Sesto Calende | 315.52 mi (507.78 km) |
| Ascoli Piceno to Sesto Fiorentino | 137.68 mi (221.58 km) |
| Ascoli Piceno to Sesto San Giovanni | 284.20 mi (457.38 km) |
| Ascoli Piceno to Sestri Levante | 231.65 mi (372.81 km) |
| Ascoli Piceno to Sestu | 338.89 mi (545.39 km) |
