| Ashtabula to Enumclaw (Washington) | 2,037.10 mi (3,278.39 km) |
| Ashtabula to Ephrata (Pennsylvania) | 267.72 mi (430.85 km) |
| Ashtabula to Erie (Colorado) | 1,266.97 mi (2,038.98 km) |
| Ashtabula to Erie (Pennsylvania) | 40.65 mi (65.42 km) |
| Ashtabula to Erlanger (Kentucky) | 280.98 mi (452.20 km) |
| Ashtabula to Escanaba (Michigan) | 411.83 mi (662.77 km) |
| Ashtabula to Escondido (California) | 2,060.75 mi (3,316.45 km) |
| Ashtabula to Española (New Mexico) | 1,411.49 mi (2,271.57 km) |
| Ashtabula to Essex (Maryland) | 289.61 mi (466.08 km) |
| Ashtabula to Essex Junction (Vermont) | 426.83 mi (686.91 km) |
| Ashtabula to Estelle (Louisiana) | 979.88 mi (1,576.97 km) |
| Ashtabula to Estero (Florida) | 1,069.19 mi (1,720.69 km) |
| Ashtabula to Euclid (Ohio) | 42.21 mi (67.93 km) |
| Ashtabula to Eufaula (Alabama) | 729.37 mi (1,173.81 km) |
| Ashtabula to Eugene (Oregon) | 2,121.22 mi (3,413.78 km) |
