| Astoria to Santa Rosa (California) | 537.69 mi (865.33 km) |
| Astoria to Santaquin (Utah) | 741.55 mi (1,193.41 km) |
| Astoria to Santee (California) | 989.21 mi (1,591.99 km) |
| Astoria to Sapulpa (Oklahoma) | 1,593.63 mi (2,564.70 km) |
| Astoria to Saraland (Alabama) | 2,176.29 mi (3,502.40 km) |
| Astoria to Sarasota (Florida) | 2,588.86 mi (4,166.37 km) |
| Astoria to Sarasota Springs (Florida) | 2,593.39 mi (4,173.66 km) |
| Astoria to Saratoga (California) | 622.86 mi (1,002.40 km) |
| Astoria to Saratoga Springs (New York) | 2,428.54 mi (3,908.35 km) |
| Astoria to Saratoga Springs (Utah) | 720.40 mi (1,159.37 km) |
| Astoria to Sartell (Minnesota) | 1,414.74 mi (2,276.80 km) |
| Astoria to Satellite Beach (Florida) | 2,641.08 mi (4,250.41 km) |
| Astoria to Sauk Rapids (Minnesota) | 1,418.20 mi (2,282.37 km) |
| Astoria to Sault Ste. Marie (Michigan) | 1,861.49 mi (2,995.77 km) |
| Astoria to Savage (Minnesota) | 1,469.29 mi (2,364.59 km) |
