| Astoria to Seymour (Tennessee) | 2,178.41 mi (3,505.82 km) |
| Astoria to Shady Hills (Florida) | 2,540.56 mi (4,088.64 km) |
| Astoria to Shafter (California) | 777.54 mi (1,251.33 km) |
| Astoria to Shaker Heights (Ohio) | 2,105.77 mi (3,388.91 km) |
| Astoria to Shakopee (Minnesota) | 1,463.53 mi (2,355.32 km) |
| Astoria to Sharon (Pennsylvania) | 2,162.31 mi (3,479.90 km) |
| Astoria to Sharonville (Ohio) | 2,033.28 mi (3,272.25 km) |
| Astoria to Shasta Lake (California) | 387.14 mi (623.04 km) |
| Astoria to Shawnee (Kansas) | 1,545.60 mi (2,487.41 km) |
| Astoria to Shawnee (Oklahoma) | 1,580.59 mi (2,543.71 km) |
| Astoria to Sheboygan (Wisconsin) | 1,756.38 mi (2,826.61 km) |
| Astoria to Shelby (North Carolina) | 2,305.87 mi (3,710.94 km) |
| Astoria to Shelbyville (Indiana) | 1,959.89 mi (3,154.14 km) |
| Astoria to Shelbyville (Kentucky) | 2,028.19 mi (3,264.06 km) |
| Astoria to Shelbyville (Tennessee) | 2,064.63 mi (3,322.69 km) |
