| Astoria to Smyrna (Delaware) | 2,452.76 mi (3,947.33 km) |
| Astoria to Smyrna (Georgia) | 2,218.66 mi (3,570.58 km) |
| Astoria to Smyrna (Tennessee) | 2,043.78 mi (3,289.15 km) |
| Astoria to Snellville (Georgia) | 2,243.22 mi (3,610.11 km) |
| Astoria to Snoqualmie (Washington) | 131.26 mi (211.24 km) |
| Astoria to Snyder (Texas) | 1,526.24 mi (2,456.25 km) |
| Astoria to Socastee (South Carolina) | 2,487.35 mi (4,003.01 km) |
| Astoria to Socorro (Texas) | 1,372.26 mi (2,208.43 km) |
| Astoria to Soddy-Daisy (Tennessee) | 2,134.27 mi (3,434.77 km) |
| Astoria to Solana Beach (California) | 974.97 mi (1,569.06 km) |
| Astoria to Soledad (California) | 685.06 mi (1,102.50 km) |
| Astoria to Solon (Ohio) | 2,113.40 mi (3,401.18 km) |
| Astoria to Somers Point (New Jersey) | 2,499.59 mi (4,022.71 km) |
| Astoria to Somerset (Kentucky) | 2,095.52 mi (3,372.41 km) |
| Astoria to Somerset (New Jersey) | 2,467.63 mi (3,971.27 km) |
