| Astoria to Storm Lake (Iowa) | 1,425.00 mi (2,293.31 km) |
| Astoria to Storrs (Connecticut) | 2,534.88 mi (4,079.49 km) |
| Astoria to Stoughton (Wisconsin) | 1,703.81 mi (2,742.02 km) |
| Astoria to Stow (Ohio) | 2,119.49 mi (3,410.99 km) |
| Astoria to Streamwood (Illinois) | 1,775.59 mi (2,857.54 km) |
| Astoria to Streator (Illinois) | 1,768.05 mi (2,845.40 km) |
| Astoria to Streetsboro (Ohio) | 2,121.96 mi (3,414.96 km) |
| Astoria to Strongsville (Ohio) | 2,096.83 mi (3,374.52 km) |
| Astoria to Stuart (Florida) | 2,701.74 mi (4,348.04 km) |
| Astoria to Stuarts Draft (Virginia) | 2,330.58 mi (3,750.70 km) |
| Astoria to Sturgis (Michigan) | 1,912.94 mi (3,078.58 km) |
| Astoria to Suamico (Wisconsin) | 1,722.05 mi (2,771.37 km) |
| Astoria to Sudley (Virginia) | 2,379.01 mi (3,828.65 km) |
| Astoria to Suffern (New York) | 2,466.48 mi (3,969.41 km) |
| Astoria to Suffolk (Virginia) | 2,490.10 mi (4,007.43 km) |
