| Aylesbury to Sacile | 725.67 mi (1,167.86 km) |
| Aylesbury to Sala Consilina | 1,108.80 mi (1,784.45 km) |
| Aylesbury to Salemi | 1,170.88 mi (1,884.36 km) |
| Aylesbury to Salerno | 1,066.01 mi (1,715.58 km) |
| Aylesbury to Salo | 671.06 mi (1,079.97 km) |
| Aylesbury to Salsomaggiore Terme | 691.43 mi (1,112.75 km) |
| Aylesbury to Saluzzo | 624.91 mi (1,005.69 km) |
| Aylesbury to Salzano | 730.69 mi (1,175.93 km) |
| Aylesbury to Samarate | 611.31 mi (983.80 km) |
| Aylesbury to San Benedetto del Tronto | 917.76 mi (1,476.99 km) |
| Aylesbury to San Biagio di Callalta | 733.52 mi (1,180.49 km) |
| Aylesbury to San Bonifacio | 706.91 mi (1,137.67 km) |
| Aylesbury to San Casciano in Val di Pesa | 790.98 mi (1,272.95 km) |
| Aylesbury to San Cataldo | 1,223.67 mi (1,969.31 km) |
| Aylesbury to San Cesareo | 941.27 mi (1,514.82 km) |
