| Ayr to Sestu | 1,282.59 mi (2,064.12 km) |
| Ayr to Settimo Torinese | 896.22 mi (1,442.33 km) |
| Ayr to Seveso | 905.10 mi (1,456.62 km) |
| Ayr to Sezze | 1,252.32 mi (2,015.42 km) |
| Ayr to Siano | 1,339.66 mi (2,155.98 km) |
| Ayr to Siena | 1,098.67 mi (1,768.13 km) |
| Ayr to Signa | 1,065.70 mi (1,715.08 km) |
| Ayr to Silea | 1,000.54 mi (1,610.22 km) |
| Ayr to Silvi Paese | 1,224.11 mi (1,970.02 km) |
| Ayr to Sinalunga | 1,115.99 mi (1,796.01 km) |
| Ayr to Siniscola | 1,217.78 mi (1,959.83 km) |
| Ayr to Sinnai | 1,284.91 mi (2,067.86 km) |
| Ayr to Siracusa | 1,575.17 mi (2,534.99 km) |
| Ayr to Solaro | 905.14 mi (1,456.69 km) |
| Ayr to Soliera | 1,007.35 mi (1,621.17 km) |
