| Big Spring to Indianola (Iowa) | 766.78 mi (1,234.01 km) |
| Big Spring to Indio (California) | 860.58 mi (1,384.97 km) |
| Big Spring to Inglewood (California) | 982.21 mi (1,580.72 km) |
| Big Spring to Inkster (Michigan) | 1,212.51 mi (1,951.35 km) |
| Big Spring to Inver Grove Heights (Minnesota) | 980.18 mi (1,577.44 km) |
| Big Spring to Inwood (New York) | 1,638.27 mi (2,636.55 km) |
| Big Spring to Iona (Florida) | 1,237.78 mi (1,992.01 km) |
| Big Spring to Ionia (Michigan) | 1,161.19 mi (1,868.76 km) |
| Big Spring to Iowa City (Iowa) | 850.34 mi (1,368.49 km) |
| Big Spring to Irmo (South Carolina) | 1,178.21 mi (1,896.15 km) |
| Big Spring to Irondale (Alabama) | 863.75 mi (1,390.07 km) |
| Big Spring to Ironton (Ohio) | 1,142.18 mi (1,838.16 km) |
| Big Spring to Irvine (California) | 948.84 mi (1,527.01 km) |
| Big Spring to Irving (Texas) | 266.09 mi (428.23 km) |
| Big Spring to Isabela (Puerto Rico) | 2,337.77 mi (3,762.27 km) |
