| Big Spring to Medford (New York) | 1,680.29 mi (2,704.16 km) |
| Big Spring to Medford (Oregon) | 1,360.73 mi (2,189.88 km) |
| Big Spring to Medina (Ohio) | 1,244.18 mi (2,002.31 km) |
| Big Spring to Medulla (Florida) | 1,200.32 mi (1,931.73 km) |
| Big Spring to Mehlville (Missouri) | 762.58 mi (1,227.26 km) |
| Big Spring to Melbourne (Florida) | 1,273.54 mi (2,049.56 km) |
| Big Spring to Melissa (Texas) | 295.04 mi (474.81 km) |
| Big Spring to Melrose (Massachusetts) | 1,801.52 mi (2,899.26 km) |
| Big Spring to Melrose Park (Illinois) | 1,002.36 mi (1,613.15 km) |
| Big Spring to Melville (New York) | 1,658.07 mi (2,668.41 km) |
| Big Spring to Melvindale (Michigan) | 1,218.18 mi (1,960.48 km) |
| Big Spring to Memphis (Florida) | 1,176.97 mi (1,894.14 km) |
| Big Spring to Memphis (Tennessee) | 690.60 mi (1,111.42 km) |
| Big Spring to Menasha (Wisconsin) | 1,086.41 mi (1,748.41 km) |
| Big Spring to Mendota (California) | 1,118.28 mi (1,799.69 km) |
