| Big Spring to Odessa (Texas) | 56.39 mi (90.75 km) |
| Big Spring to Ogden (Utah) | 849.03 mi (1,366.38 km) |
| Big Spring to Oildale (California) | 1,029.62 mi (1,657.01 km) |
| Big Spring to Ojus (Florida) | 1,355.48 mi (2,181.43 km) |
| Big Spring to Okemos (Michigan) | 1,178.84 mi (1,897.15 km) |
| Big Spring to Oklahoma City (Oklahoma) | 318.62 mi (512.78 km) |
| Big Spring to Okmulgee (Oklahoma) | 390.80 mi (628.94 km) |
| Big Spring to Olathe (Kansas) | 591.97 mi (952.69 km) |
| Big Spring to Old Jamestown (Missouri) | 776.28 mi (1,249.31 km) |
| Big Spring to Oldsmar (Florida) | 1,158.81 mi (1,864.93 km) |
| Big Spring to Olean (New York) | 1,433.29 mi (2,306.66 km) |
| Big Spring to Olive Branch (Mississippi) | 694.91 mi (1,118.35 km) |
| Big Spring to Olivehurst (California) | 1,218.76 mi (1,961.41 km) |
| Big Spring to Olney (Maryland) | 1,445.07 mi (2,325.61 km) |
| Big Spring to Olympia (Washington) | 1,521.86 mi (2,449.20 km) |
