| Big Spring to Orangevale (California) | 1,193.86 mi (1,921.33 km) |
| Big Spring to Orchards (Washington) | 1,455.81 mi (2,342.90 km) |
| Big Spring to Orcutt (California) | 1,104.01 mi (1,776.73 km) |
| Big Spring to Oregon (Ohio) | 1,186.26 mi (1,909.10 km) |
| Big Spring to Oregon (Wisconsin) | 989.60 mi (1,592.61 km) |
| Big Spring to Oregon City (Oregon) | 1,445.68 mi (2,326.59 km) |
| Big Spring to Orem (Utah) | 795.28 mi (1,279.87 km) |
| Big Spring to Orinda (California) | 1,230.74 mi (1,980.68 km) |
| Big Spring to Orland Park (Illinois) | 990.18 mi (1,593.54 km) |
| Big Spring to Orlando (Florida) | 1,226.72 mi (1,974.22 km) |
| Big Spring to Ormond Beach (Florida) | 1,224.83 mi (1,971.18 km) |
| Big Spring to Oro Valley (Arizona) | 554.41 mi (892.23 km) |
| Big Spring to Oroville (California) | 1,227.72 mi (1,975.83 km) |
| Big Spring to Oshkosh (Wisconsin) | 1,072.40 mi (1,725.87 km) |
| Big Spring to Oskaloosa (Iowa) | 793.19 mi (1,276.52 km) |
