| Big Spring to Saddlebrooke (Arizona) | 548.30 mi (882.41 km) |
| Big Spring to Safety Harbor (Florida) | 1,158.25 mi (1,864.02 km) |
| Big Spring to Saginaw (Michigan) | 1,225.20 mi (1,971.76 km) |
| Big Spring to Saginaw (Texas) | 243.49 mi (391.86 km) |
| Big Spring to Sahuarita (Arizona) | 555.50 mi (893.99 km) |
| Big Spring to Saks (Alabama) | 910.56 mi (1,465.40 km) |
| Big Spring to Salem (Massachusetts) | 1,810.19 mi (2,913.23 km) |
| Big Spring to Salem (Ohio) | 1,287.38 mi (2,071.84 km) |
| Big Spring to Salem (Oregon) | 1,449.07 mi (2,332.05 km) |
| Big Spring to Salem (Virginia) | 1,261.94 mi (2,030.90 km) |
| Big Spring to Salem Lakes (Wisconsin) | 1,019.03 mi (1,639.96 km) |
| Big Spring to Salida (California) | 1,169.80 mi (1,882.62 km) |
| Big Spring to Salina (Kansas) | 503.46 mi (810.24 km) |
| Big Spring to Salinas (California) | 1,185.91 mi (1,908.53 km) |
| Big Spring to Salisbury (Maryland) | 1,514.59 mi (2,437.49 km) |
