| Big Spring to San Luis Obispo (California) | 1,120.16 mi (1,802.73 km) |
| Big Spring to San Marcos (California) | 913.89 mi (1,470.77 km) |
| Big Spring to San Marcos (Texas) | 265.91 mi (427.93 km) |
| Big Spring to San Marino (California) | 969.52 mi (1,560.29 km) |
| Big Spring to San Mateo (California) | 1,233.28 mi (1,984.77 km) |
| Big Spring to San Pablo (California) | 1,240.66 mi (1,996.65 km) |
| Big Spring to San Rafael (California) | 1,250.62 mi (2,012.67 km) |
| Big Spring to San Ramon (California) | 1,216.08 mi (1,957.08 km) |
| Big Spring to San Tan Valley (Arizona) | 589.55 mi (948.78 km) |
| Big Spring to Sand Springs (Oklahoma) | 407.34 mi (655.55 km) |
| Big Spring to Sandusky (Ohio) | 1,213.70 mi (1,953.26 km) |
| Big Spring to Sandy (Oregon) | 1,434.44 mi (2,308.50 km) |
| Big Spring to Sandy (Utah) | 813.72 mi (1,309.56 km) |
| Big Spring to Sandy Springs (Georgia) | 996.20 mi (1,603.23 km) |
| Big Spring to Sanford (Florida) | 1,224.08 mi (1,969.96 km) |
