| Big Spring to Sanford (Maine) | 1,832.29 mi (2,948.78 km) |
| Big Spring to Sanford (North Carolina) | 1,296.23 mi (2,086.08 km) |
| Big Spring to Sanger (California) | 1,072.95 mi (1,726.75 km) |
| Big Spring to Santa Ana (California) | 955.16 mi (1,537.19 km) |
| Big Spring to Santa Barbara (California) | 1,062.28 mi (1,709.57 km) |
| Big Spring to Santa Clara (California) | 1,212.28 mi (1,950.98 km) |
| Big Spring to Santa Clara (Oregon) | 1,426.95 mi (2,296.45 km) |
| Big Spring to Santa Clarita (California) | 992.61 mi (1,597.45 km) |
| Big Spring to Santa Cruz (California) | 1,211.15 mi (1,949.17 km) |
| Big Spring to Santa Fe (New Mexico) | 349.94 mi (563.17 km) |
| Big Spring to Santa Fe (Texas) | 426.60 mi (686.54 km) |
| Big Spring to Santa Fe Springs (California) | 966.00 mi (1,554.63 km) |
| Big Spring to Santa Maria (California) | 1,105.51 mi (1,779.15 km) |
| Big Spring to Santa Monica (California) | 990.22 mi (1,593.60 km) |
| Big Spring to Santa Paula (California) | 1,024.73 mi (1,649.14 km) |
