| Big Spring to Security-Widefield (Colorado) | 485.11 mi (780.70 km) |
| Big Spring to Sedalia (Missouri) | 643.61 mi (1,035.80 km) |
| Big Spring to Sedro-Woolley (Washington) | 1,557.62 mi (2,506.75 km) |
| Big Spring to Seguin (Texas) | 277.21 mi (446.13 km) |
| Big Spring to Selden (New York) | 1,677.87 mi (2,700.27 km) |
| Big Spring to Selma (Alabama) | 842.88 mi (1,356.48 km) |
| Big Spring to Selma (California) | 1,074.34 mi (1,728.99 km) |
| Big Spring to Selma (Texas) | 262.31 mi (422.14 km) |
| Big Spring to Seminole (Florida) | 1,157.00 mi (1,862.01 km) |
| Big Spring to Seven Hills (Ohio) | 1,260.25 mi (2,028.17 km) |
| Big Spring to Seven Oaks (South Carolina) | 1,181.16 mi (1,900.90 km) |
| Big Spring to Severn (Maryland) | 1,464.65 mi (2,357.13 km) |
| Big Spring to Severna Park (Maryland) | 1,470.68 mi (2,366.83 km) |
| Big Spring to Sevierville (Tennessee) | 1,054.11 mi (1,696.43 km) |
| Big Spring to Seymour (Indiana) | 989.01 mi (1,591.65 km) |
