| Big Spring to Seymour (Tennessee) | 1,043.00 mi (1,678.55 km) |
| Big Spring to Shady Hills (Florida) | 1,158.17 mi (1,863.89 km) |
| Big Spring to Shafter (California) | 1,039.59 mi (1,673.06 km) |
| Big Spring to Shaker Heights (Ohio) | 1,268.74 mi (2,041.84 km) |
| Big Spring to Shakopee (Minnesota) | 967.01 mi (1,556.25 km) |
| Big Spring to Sharon (Pennsylvania) | 1,312.61 mi (2,112.43 km) |
| Big Spring to Sharonville (Ohio) | 1,071.37 mi (1,724.20 km) |
| Big Spring to Shasta Lake (California) | 1,294.95 mi (2,084.02 km) |
| Big Spring to Shawnee (Kansas) | 599.33 mi (964.52 km) |
| Big Spring to Shawnee (Oklahoma) | 336.84 mi (542.09 km) |
| Big Spring to Sheboygan (Wisconsin) | 1,088.86 mi (1,752.35 km) |
| Big Spring to Shelby (North Carolina) | 1,162.21 mi (1,870.39 km) |
| Big Spring to Shelbyville (Indiana) | 1,011.05 mi (1,627.13 km) |
| Big Spring to Shelbyville (Kentucky) | 1,003.78 mi (1,615.43 km) |
| Big Spring to Shelbyville (Tennessee) | 890.08 mi (1,432.45 km) |
