| Big Spring to Smyrna (Delaware) | 1,523.87 mi (2,452.44 km) |
| Big Spring to Smyrna (Georgia) | 987.63 mi (1,589.44 km) |
| Big Spring to Smyrna (Tennessee) | 892.40 mi (1,436.17 km) |
| Big Spring to Snellville (Georgia) | 1,017.04 mi (1,636.77 km) |
| Big Spring to Snoqualmie (Washington) | 1,501.63 mi (2,416.65 km) |
| Big Spring to Snyder (Texas) | 46.60 mi (75.00 km) |
| Big Spring to Socastee (South Carolina) | 1,303.95 mi (2,098.50 km) |
| Big Spring to Socorro (Texas) | 283.31 mi (455.94 km) |
| Big Spring to Soddy-Daisy (Tennessee) | 958.51 mi (1,542.57 km) |
| Big Spring to Solana Beach (California) | 918.83 mi (1,478.71 km) |
| Big Spring to Soledad (California) | 1,167.45 mi (1,878.83 km) |
| Big Spring to Solon (Ohio) | 1,271.52 mi (2,046.31 km) |
| Big Spring to Somers Point (New Jersey) | 1,576.87 mi (2,537.73 km) |
| Big Spring to Somerset (Kentucky) | 1,013.72 mi (1,631.42 km) |
| Big Spring to Somerset (New Jersey) | 1,598.12 mi (2,571.92 km) |
