| Big Spring to St. George (Utah) | 763.54 mi (1,228.79 km) |
| Big Spring to St. Helens (Oregon) | 1,473.66 mi (2,371.62 km) |
| Big Spring to St. James (New York) | 1,672.54 mi (2,691.69 km) |
| Big Spring to St. John (Indiana) | 1,000.01 mi (1,609.37 km) |
| Big Spring to St. Joseph (Missouri) | 638.76 mi (1,027.98 km) |
| Big Spring to St. Louis (Missouri) | 770.63 mi (1,240.21 km) |
| Big Spring to St. Louis Park (Minnesota) | 980.20 mi (1,577.49 km) |
| Big Spring to St. Marys (Georgia) | 1,175.60 mi (1,891.95 km) |
| Big Spring to St. Marys (Pennsylvania) | 1,413.53 mi (2,274.86 km) |
| Big Spring to St. Matthews (Kentucky) | 983.88 mi (1,583.40 km) |
| Big Spring to St. Michael (Minnesota) | 987.97 mi (1,589.98 km) |
| Big Spring to St. Paul (Minnesota) | 986.44 mi (1,587.53 km) |
| Big Spring to St. Peter (Minnesota) | 928.48 mi (1,494.24 km) |
| Big Spring to St. Peters (Missouri) | 759.62 mi (1,222.49 km) |
| Big Spring to St. Petersburg (Florida) | 1,165.01 mi (1,874.90 km) |
