| Big Spring to St. Simons (Georgia) | 1,181.70 mi (1,901.75 km) |
| Big Spring to Stafford (Texas) | 394.16 mi (634.34 km) |
| Big Spring to Stallings (North Carolina) | 1,211.16 mi (1,949.18 km) |
| Big Spring to Stamford (Connecticut) | 1,655.17 mi (2,663.73 km) |
| Big Spring to Stanford (California) | 1,223.82 mi (1,969.55 km) |
| Big Spring to Stanton (California) | 961.71 mi (1,547.72 km) |
| Big Spring to Star (Idaho) | 1,134.96 mi (1,826.54 km) |
| Big Spring to Starkville (Mississippi) | 738.65 mi (1,188.74 km) |
| Big Spring to State College (Pennsylvania) | 1,432.76 mi (2,305.81 km) |
| Big Spring to Staten Island (New York) | 1,617.25 mi (2,602.71 km) |
| Big Spring to Statesboro (Georgia) | 1,148.76 mi (1,848.75 km) |
| Big Spring to Statesville (North Carolina) | 1,203.07 mi (1,936.15 km) |
| Big Spring to Staunton (Virginia) | 1,326.30 mi (2,134.47 km) |
| Big Spring to Steamboat Springs (Colorado) | 641.91 mi (1,033.06 km) |
| Big Spring to Steiner Ranch (Texas) | 248.01 mi (399.14 km) |
