| Big Spring to Stephenville (Texas) | 190.51 mi (306.59 km) |
| Big Spring to Sterling (Colorado) | 586.85 mi (944.44 km) |
| Big Spring to Sterling (Illinois) | 925.09 mi (1,488.79 km) |
| Big Spring to Sterling (Virginia) | 1,425.57 mi (2,294.23 km) |
| Big Spring to Sterling Heights (Michigan) | 1,234.85 mi (1,987.29 km) |
| Big Spring to Steubenville (Ohio) | 1,284.19 mi (2,066.71 km) |
| Big Spring to Stevens Point (Wisconsin) | 1,064.31 mi (1,712.84 km) |
| Big Spring to Stevenson Ranch (California) | 997.71 mi (1,605.65 km) |
| Big Spring to Stillwater (Minnesota) | 999.69 mi (1,608.85 km) |
| Big Spring to Stillwater (Oklahoma) | 368.35 mi (592.81 km) |
| Big Spring to Stockbridge (Georgia) | 1,003.71 mi (1,615.31 km) |
| Big Spring to Stockton (California) | 1,186.09 mi (1,908.83 km) |
| Big Spring to Stone Ridge (Virginia) | 1,416.58 mi (2,279.77 km) |
| Big Spring to Stonecrest (Georgia) | 1,009.14 mi (1,624.05 km) |
| Big Spring to Stony Brook (New York) | 1,674.20 mi (2,694.37 km) |
