| Big Spring to Superior (Colorado) | 569.83 mi (917.06 km) |
| Big Spring to Superior (Wisconsin) | 1,115.57 mi (1,795.34 km) |
| Big Spring to Surprise (Arizona) | 643.49 mi (1,035.60 km) |
| Big Spring to Susanville (California) | 1,202.10 mi (1,934.59 km) |
| Big Spring to Sussex (Wisconsin) | 1,042.54 mi (1,677.80 km) |
| Big Spring to Suwanee (Georgia) | 1,013.76 mi (1,631.49 km) |
| Big Spring to Swansea (Illinois) | 779.59 mi (1,254.63 km) |
| Big Spring to Sweetwater (Florida) | 1,348.23 mi (2,169.76 km) |
| Big Spring to Sweetwater (Texas) | 64.49 mi (103.78 km) |
| Big Spring to Sycamore (Illinois) | 973.44 mi (1,566.60 km) |
| Big Spring to Sylacauga (Alabama) | 886.41 mi (1,426.53 km) |
| Big Spring to Sylvania (Ohio) | 1,175.46 mi (1,891.72 km) |
| Big Spring to Syosset (New York) | 1,653.78 mi (2,661.50 km) |
| Big Spring to Syracuse (New York) | 1,565.53 mi (2,519.48 km) |
| Big Spring to Syracuse (Utah) | 846.15 mi (1,361.75 km) |
