| Big Spring to University Place (Washington) | 1,515.26 mi (2,438.58 km) |
| Big Spring to Upland (California) | 943.64 mi (1,518.65 km) |
| Big Spring to Upper Arlington (Ohio) | 1,156.52 mi (1,861.23 km) |
| Big Spring to Upper Grand Lagoon (Florida) | 940.19 mi (1,513.09 km) |
| Big Spring to Upper Montclair (New Jersey) | 1,618.52 mi (2,604.76 km) |
| Big Spring to Urbana (Illinois) | 917.34 mi (1,476.32 km) |
| Big Spring to Urbana (Maryland) | 1,433.52 mi (2,307.02 km) |
| Big Spring to Urbana (Ohio) | 1,125.31 mi (1,811.01 km) |
| Big Spring to Urbandale (Iowa) | 775.50 mi (1,248.04 km) |
| Big Spring to Utica (New York) | 1,610.47 mi (2,591.81 km) |
| Big Spring to Uvalde (Texas) | 232.07 mi (373.48 km) |
| Big Spring to Vacaville (California) | 1,227.00 mi (1,974.67 km) |
| Big Spring to Vadnais Heights (Minnesota) | 993.69 mi (1,599.19 km) |
| Big Spring to Vail (Arizona) | 539.15 mi (867.68 km) |
| Big Spring to Valdosta (Georgia) | 1,074.74 mi (1,729.63 km) |
