| Brighton to Shotley Bridge | 288.84 mi (464.84 km) |
| Brighton to Shrewsbury | 171.79 mi (276.47 km) |
| Brighton to Sidcup | 43.11 mi (69.38 km) |
| Brighton to Sidmouth | 135.92 mi (218.74 km) |
| Brighton to Sileby | 138.32 mi (222.61 km) |
| Brighton to Sittingbourne | 52.32 mi (84.20 km) |
| Brighton to Skegness | 161.79 mi (260.37 km) |
| Brighton to Skelmersdale | 219.17 mi (352.72 km) |
| Brighton to Skipton | 231.05 mi (371.84 km) |
| Brighton to Sleaford | 150.75 mi (242.61 km) |
| Brighton to Slough | 51.36 mi (82.66 km) |
| Brighton to Small Heath | 135.23 mi (217.64 km) |
| Brighton to Smethwick | 139.67 mi (224.78 km) |
| Brighton to Snaresbrook | 53.35 mi (85.85 km) |
| Brighton to Snodland | 43.26 mi (69.62 km) |
