| Brindisi to Setubal | 1,430.41 mi (2,302.02 km) |
| Brindisi to Sever do Vouga | 1,372.81 mi (2,209.33 km) |
| Brindisi to Silves | 1,432.17 mi (2,304.86 km) |
| Brindisi to Sines | 1,439.17 mi (2,316.13 km) |
| Brindisi to Sintra | 1,451.75 mi (2,336.36 km) |
| Brindisi to Sobrado de Paiva | 1,364.77 mi (2,196.39 km) |
| Brindisi to Sobral de Monte Agraco | 1,435.88 mi (2,310.83 km) |
| Brindisi to Soure | 1,394.32 mi (2,243.94 km) |
| Brindisi to Tabua | 1,359.26 mi (2,187.52 km) |
| Brindisi to Tavira | 1,392.31 mi (2,240.70 km) |
| Brindisi to Tomar | 1,388.91 mi (2,235.23 km) |
| Brindisi to Tondela | 1,360.36 mi (2,189.29 km) |
| Brindisi to Torre de Moncorvo | 1,304.81 mi (2,099.88 km) |
| Brindisi to Torres Novas | 1,396.85 mi (2,248.02 km) |
| Brindisi to Torres Vedras | 1,440.86 mi (2,318.83 km) |
