| Brindisi to Sestao | 1,088.41 mi (1,751.63 km) |
| Brindisi to Sevilla | 1,302.71 mi (2,096.51 km) |
| Brindisi to Sevilla La Nueva | 1,151.18 mi (1,852.65 km) |
| Brindisi to Silla | 973.12 mi (1,566.09 km) |
| Brindisi to Silleda | 1,352.64 mi (2,176.87 km) |
| Brindisi to Sitges | 841.72 mi (1,354.61 km) |
| Brindisi to Socuellamos | 1,099.01 mi (1,768.68 km) |
| Brindisi to Soller | 805.13 mi (1,295.72 km) |
| Brindisi to Solsona | 855.75 mi (1,377.19 km) |
| Brindisi to Son Servera | 772.19 mi (1,242.71 km) |
| Brindisi to Sonseca | 1,154.24 mi (1,857.57 km) |
| Brindisi to Sopelana | 1,087.32 mi (1,749.88 km) |
| Brindisi to Soria | 1,060.92 mi (1,707.39 km) |
| Brindisi to Suances | 1,141.18 mi (1,836.55 km) |
| Brindisi to Sueca | 970.09 mi (1,561.22 km) |
