| Buffalo to St. Louis (Missouri) | 664.44 mi (1,069.31 km) |
| Buffalo to Atlanta (Georgia) | 699.56 mi (1,125.83 km) |
| Buffalo to Minneapolis (Minnesota) | 730.43 mi (1,175.51 km) |
| Buffalo to Tampa (Florida) | 1,049.41 mi (1,688.87 km) |
| Buffalo to Miami (Florida) | 1,185.23 mi (1,907.44 km) |
| Buffalo to Dallas (Texas) | 1,197.30 mi (1,926.88 km) |
| Buffalo to Houston (Texas) | 1,287.13 mi (2,071.43 km) |
| Buffalo to Denver (Colorado) | 1,362.04 mi (2,192.00 km) |
| Buffalo to Phoenix (Arizona) | 1,900.95 mi (3,059.28 km) |
| Buffalo to Las Vegas (Nevada) | 1,977.16 mi (3,181.93 km) |
| Buffalo to Seattle (Washington) | 2,111.00 mi (3,397.33 km) |
| Buffalo to Portland (Oregon) | 2,149.53 mi (3,459.34 km) |
| Buffalo to Riverside (California) | 2,155.69 mi (3,469.25 km) |
| Buffalo to San Diego (California) | 2,179.04 mi (3,506.83 km) |
| Buffalo to Los Angeles (California) | 2,201.12 mi (3,542.35 km) |
| Buffalo to San Francisco (California) | 2,297.62 mi (3,697.66 km) |
| Buffalo to Detroit (Michigan) | 219.11 mi (352.63 km) |
| Buffalo to Baltimore (Maryland) | 274.36 mi (441.54 km) |
| Buffalo to Philadelphia (Pennsylvania) | 277.41 mi (446.45 km) |
| Buffalo to Washington (District of Columbia) | 292.26 mi (470.35 km) |
| Buffalo to New York (New York) | 295.87 mi (476.16 km) |
| Buffalo to Brooklyn (New York) | 296.45 mi (477.09 km) |
| Buffalo to Queens (New York) | 299.49 mi (481.99 km) |
| Buffalo to Boston (Massachusetts) | 396.69 mi (638.41 km) |
| Buffalo to Chicago (Illinois) | 456.88 mi (735.28 km) |
