| Buffalo to Orbetello | 4,331.50 mi (6,970.88 km) |
| Buffalo to Oria | 4,678.60 mi (7,529.48 km) |
| Buffalo to Oristano | 4,318.05 mi (6,949.23 km) |
| Buffalo to Orta Nova | 4,564.07 mi (7,345.15 km) |
| Buffalo to Orte | 4,379.85 mi (7,048.68 km) |
| Buffalo to Ortona | 4,467.92 mi (7,190.43 km) |
| Buffalo to Orvieto | 4,358.14 mi (7,013.75 km) |
| Buffalo to Orzinuovi | 4,165.50 mi (6,703.72 km) |
| Buffalo to Osimo | 4,384.66 mi (7,056.43 km) |
| Buffalo to Ospitaletto | 4,165.45 mi (6,703.64 km) |
| Buffalo to Ostuni | 4,666.60 mi (7,510.16 km) |
| Buffalo to Ottaviano | 4,532.49 mi (7,294.33 km) |
| Buffalo to Ovada | 4,140.58 mi (6,663.62 km) |
| Buffalo to Ozieri | 4,309.50 mi (6,935.48 km) |
| Buffalo to Paceco | 4,568.29 mi (7,351.96 km) |
