| Caldas da Rainha to Sestu | 972.20 mi (1,564.61 km) |
| Caldas da Rainha to Settimo Torinese | 948.01 mi (1,525.67 km) |
| Caldas da Rainha to Seveso | 1,022.28 mi (1,645.21 km) |
| Caldas da Rainha to Sezze | 1,172.94 mi (1,887.67 km) |
| Caldas da Rainha to Siano | 1,259.16 mi (2,026.41 km) |
| Caldas da Rainha to Siena | 1,092.17 mi (1,757.67 km) |
| Caldas da Rainha to Signa | 1,085.32 mi (1,746.65 km) |
| Caldas da Rainha to Silea | 1,169.03 mi (1,881.36 km) |
| Caldas da Rainha to Silvi Paese | 1,228.15 mi (1,976.51 km) |
| Caldas da Rainha to Sinalunga | 1,111.39 mi (1,788.61 km) |
| Caldas da Rainha to Siniscola | 998.24 mi (1,606.50 km) |
| Caldas da Rainha to Sinnai | 978.09 mi (1,574.09 km) |
| Caldas da Rainha to Siracusa | 1,331.12 mi (2,142.23 km) |
| Caldas da Rainha to Solaro | 1,019.21 mi (1,640.26 km) |
| Caldas da Rainha to Soliera | 1,089.35 mi (1,753.14 km) |
