| Caldas de Reyes to Sestu | 951.01 mi (1,530.51 km) |
| Caldas de Reyes to Settimo Torinese | 834.10 mi (1,342.35 km) |
| Caldas de Reyes to Seveso | 904.27 mi (1,455.28 km) |
| Caldas de Reyes to Sezze | 1,113.11 mi (1,791.38 km) |
| Caldas de Reyes to Siano | 1,206.18 mi (1,941.16 km) |
| Caldas de Reyes to Siena | 1,008.55 mi (1,623.11 km) |
| Caldas de Reyes to Signa | 995.24 mi (1,601.68 km) |
| Caldas de Reyes to Silea | 1,056.22 mi (1,699.82 km) |
| Caldas de Reyes to Silvi Paese | 1,154.24 mi (1,857.57 km) |
| Caldas de Reyes to Sinalunga | 1,029.25 mi (1,656.41 km) |
| Caldas de Reyes to Siniscola | 955.85 mi (1,538.29 km) |
| Caldas de Reyes to Sinnai | 956.54 mi (1,539.41 km) |
| Caldas de Reyes to Siracusa | 1,320.60 mi (2,125.30 km) |
| Caldas de Reyes to Solaro | 901.46 mi (1,450.77 km) |
| Caldas de Reyes to Soliera | 986.29 mi (1,587.29 km) |
