| Cape Girardeau to Senftenberg | 4,767.74 mi (7,672.94 km) |
| Cape Girardeau to Siegburg | 4,543.71 mi (7,312.40 km) |
| Cape Girardeau to Siegen | 4,571.49 mi (7,357.10 km) |
| Cape Girardeau to Sigmaringen | 4,717.99 mi (7,592.88 km) |
| Cape Girardeau to Simbach am Inn | 4,857.44 mi (7,817.30 km) |
| Cape Girardeau to Simmerath | 4,516.24 mi (7,268.18 km) |
| Cape Girardeau to Sindelfingen | 4,686.72 mi (7,542.55 km) |
| Cape Girardeau to Sinsheim | 4,662.61 mi (7,503.74 km) |
| Cape Girardeau to Sinzheim | 4,652.52 mi (7,487.51 km) |
| Cape Girardeau to Sinzig | 4,554.37 mi (7,329.56 km) |
| Cape Girardeau to Soest | 4,550.92 mi (7,324.00 km) |
| Cape Girardeau to Solingen | 4,526.57 mi (7,284.82 km) |
| Cape Girardeau to Soltau | 4,564.09 mi (7,345.20 km) |
| Cape Girardeau to Sommerda | 4,676.46 mi (7,526.04 km) |
| Cape Girardeau to Sondershausen | 4,659.76 mi (7,499.16 km) |
