| Cape Girardeau to Santa Venerina | 5,377.27 mi (8,653.88 km) |
| Cape Girardeau to Santeramo in Colle | 5,312.62 mi (8,549.83 km) |
| Cape Girardeau to Santo Stefano di Magra | 4,893.88 mi (7,875.94 km) |
| Cape Girardeau to Santo Stino di Livenza | 4,944.24 mi (7,956.99 km) |
| Cape Girardeau to Sarezzo | 4,848.44 mi (7,802.81 km) |
| Cape Girardeau to Sarno | 5,223.08 mi (8,405.74 km) |
| Cape Girardeau to Saronno | 4,802.38 mi (7,728.68 km) |
| Cape Girardeau to Sarzana | 4,897.61 mi (7,881.94 km) |
| Cape Girardeau to Sassari | 4,969.16 mi (7,997.09 km) |
| Cape Girardeau to Sasso Marconi | 4,939.28 mi (7,949.01 km) |
| Cape Girardeau to Sassuolo | 4,914.47 mi (7,909.07 km) |
| Cape Girardeau to Sava | 5,362.64 mi (8,630.33 km) |
| Cape Girardeau to Saviano | 5,214.75 mi (8,392.32 km) |
| Cape Girardeau to Savigliano | 4,781.16 mi (7,694.53 km) |
| Cape Girardeau to Savignano sul Panaro | 4,927.21 mi (7,929.58 km) |
