| Cape Girardeau to Savignano sul Rubicone | 4,998.03 mi (8,043.55 km) |
| Cape Girardeau to Savona | 4,829.09 mi (7,771.67 km) |
| Cape Girardeau to Scafati | 5,221.91 mi (8,403.86 km) |
| Cape Girardeau to Scalea | 5,314.64 mi (8,553.09 km) |
| Cape Girardeau to Scandiano | 4,908.90 mi (7,900.11 km) |
| Cape Girardeau to Scandicci | 4,962.13 mi (7,985.78 km) |
| Cape Girardeau to Schio | 4,892.39 mi (7,873.55 km) |
| Cape Girardeau to Sciacca | 5,295.92 mi (8,522.97 km) |
| Cape Girardeau to Scicli | 5,396.60 mi (8,684.98 km) |
| Cape Girardeau to Scordia | 5,381.36 mi (8,660.46 km) |
| Cape Girardeau to Scorze | 4,927.84 mi (7,930.59 km) |
| Cape Girardeau to Sedico | 4,906.11 mi (7,895.62 km) |
| Cape Girardeau to Sedriano | 4,804.86 mi (7,732.67 km) |
| Cape Girardeau to Segni | 5,120.66 mi (8,240.91 km) |
| Cape Girardeau to Segrate | 4,817.96 mi (7,753.75 km) |
