| Cape Girardeau to Selargius | 5,052.95 mi (8,131.94 km) |
| Cape Girardeau to Selvazzano Dentro | 4,922.26 mi (7,921.62 km) |
| Cape Girardeau to Senago | 4,807.87 mi (7,737.52 km) |
| Cape Girardeau to Senigallia | 5,046.51 mi (8,121.57 km) |
| Cape Girardeau to Seravezza | 4,913.25 mi (7,907.11 km) |
| Cape Girardeau to Seregno | 4,808.06 mi (7,737.83 km) |
| Cape Girardeau to Seriate | 4,827.69 mi (7,769.41 km) |
| Cape Girardeau to Sermoneta | 5,124.71 mi (8,247.42 km) |
| Cape Girardeau to Serramanna | 5,035.81 mi (8,104.35 km) |
| Cape Girardeau to Serravalle Pistoiese | 4,941.81 mi (7,953.07 km) |
| Cape Girardeau to Sessa Aurunca | 5,177.31 mi (8,332.08 km) |
| Cape Girardeau to Sesto Calende | 4,781.96 mi (7,695.82 km) |
| Cape Girardeau to Sesto Fiorentino | 4,959.47 mi (7,981.49 km) |
| Cape Girardeau to Sesto San Giovanni | 4,813.81 mi (7,747.07 km) |
| Cape Girardeau to Sestri Levante | 4,868.13 mi (7,834.49 km) |
