| Cape Girardeau to Ede | 4,443.77 mi (7,151.56 km) |
| Cape Girardeau to Eemnes | 4,421.66 mi (7,115.98 km) |
| Cape Girardeau to Eerbeek | 4,456.73 mi (7,172.41 km) |
| Cape Girardeau to Eersel | 4,453.70 mi (7,167.54 km) |
| Cape Girardeau to Eijsden | 4,487.65 mi (7,222.17 km) |
| Cape Girardeau to Eindhoven | 4,457.25 mi (7,173.25 km) |
| Cape Girardeau to Elburg | 4,437.41 mi (7,141.33 km) |
| Cape Girardeau to Emmeloord | 4,425.23 mi (7,121.72 km) |
| Cape Girardeau to Emmen | 4,464.98 mi (7,185.69 km) |
| Cape Girardeau to Enkhuizen | 4,408.90 mi (7,095.44 km) |
| Cape Girardeau to Enschede | 4,484.02 mi (7,216.34 km) |
| Cape Girardeau to Epe | 4,445.65 mi (7,154.58 km) |
| Cape Girardeau to Ermelo | 4,433.69 mi (7,135.33 km) |
| Cape Girardeau to Etten-Leur | 4,420.70 mi (7,114.43 km) |
| Cape Girardeau to Franeker | 4,401.29 mi (7,083.19 km) |
