| Cape Girardeau to Sesimbra | 4,235.94 mi (6,817.09 km) |
| Cape Girardeau to Setubal | 4,243.46 mi (6,829.18 km) |
| Cape Girardeau to Sever do Vouga | 4,201.12 mi (6,761.05 km) |
| Cape Girardeau to Silves | 4,307.54 mi (6,932.32 km) |
| Cape Girardeau to Sines | 4,262.56 mi (6,859.93 km) |
| Cape Girardeau to Sintra | 4,211.05 mi (6,777.03 km) |
| Cape Girardeau to Sobrado de Paiva | 4,196.82 mi (6,754.13 km) |
| Cape Girardeau to Sobral de Monte Agraco | 4,215.74 mi (6,784.58 km) |
| Cape Girardeau to Soure | 4,209.12 mi (6,773.93 km) |
| Cape Girardeau to Tabua | 4,228.33 mi (6,804.85 km) |
| Cape Girardeau to Tavira | 4,348.28 mi (6,997.87 km) |
| Cape Girardeau to Tomar | 4,233.15 mi (6,812.60 km) |
| Cape Girardeau to Tondela | 4,221.03 mi (6,793.09 km) |
| Cape Girardeau to Torre de Moncorvo | 4,244.85 mi (6,831.43 km) |
| Cape Girardeau to Torres Novas | 4,231.67 mi (6,810.22 km) |
