| Cape Girardeau to Enniskillen | 3,876.49 mi (6,238.61 km) |
| Cape Girardeau to Epping | 4,243.02 mi (6,828.47 km) |
| Cape Girardeau to Epsom | 4,239.04 mi (6,822.07 km) |
| Cape Girardeau to Erdington | 4,144.36 mi (6,669.70 km) |
| Cape Girardeau to Erith | 4,252.17 mi (6,843.21 km) |
| Cape Girardeau to Esher | 4,234.24 mi (6,814.35 km) |
| Cape Girardeau to Euxton | 4,081.89 mi (6,569.17 km) |
| Cape Girardeau to Evesham | 4,152.00 mi (6,682.00 km) |
| Cape Girardeau to Evington | 4,171.13 mi (6,712.78 km) |
| Cape Girardeau to Ewell | 4,239.33 mi (6,822.54 km) |
| Cape Girardeau to Exeter | 4,127.01 mi (6,641.78 km) |
| Cape Girardeau to Exmouth | 4,134.48 mi (6,653.80 km) |
| Cape Girardeau to Failsworth | 4,105.48 mi (6,607.12 km) |
| Cape Girardeau to Falkirk | 3,982.36 mi (6,408.98 km) |
| Cape Girardeau to Falmouth | 4,079.97 mi (6,566.08 km) |
