| Cape Girardeau to Alachua (Florida) | 660.56 mi (1,063.07 km) |
| Cape Girardeau to Alafaya (Florida) | 776.48 mi (1,249.62 km) |
| Cape Girardeau to Alameda (California) | 1,782.99 mi (2,869.44 km) |
| Cape Girardeau to Alamo (California) | 1,768.37 mi (2,845.92 km) |
| Cape Girardeau to Alamo (Texas) | 917.80 mi (1,477.06 km) |
| Cape Girardeau to Alamogordo (New Mexico) | 974.87 mi (1,568.90 km) |
| Cape Girardeau to Albany (California) | 1,783.53 mi (2,870.32 km) |
| Cape Girardeau to Albany (Georgia) | 500.80 mi (805.97 km) |
| Cape Girardeau to Albany (New York) | 910.86 mi (1,465.88 km) |
| Cape Girardeau to Albany (Oregon) | 1,806.92 mi (2,907.96 km) |
| Cape Girardeau to Albemarle (North Carolina) | 538.32 mi (866.34 km) |
| Cape Girardeau to Albert Lea (Minnesota) | 481.63 mi (775.10 km) |
| Cape Girardeau to Albertville (Alabama) | 282.04 mi (453.90 km) |
| Cape Girardeau to Albuquerque (New Mexico) | 963.32 mi (1,550.32 km) |
| Cape Girardeau to Alcoa (Tennessee) | 326.80 mi (525.94 km) |
