| Cape Girardeau to Allison Park (Pennsylvania) | 562.55 mi (905.33 km) |
| Cape Girardeau to Allouez (Wisconsin) | 501.21 mi (806.62 km) |
| Cape Girardeau to Aloha (Oregon) | 1,801.70 mi (2,899.56 km) |
| Cape Girardeau to Alpena (Michigan) | 623.20 mi (1,002.95 km) |
| Cape Girardeau to Alpharetta (Georgia) | 371.53 mi (597.92 km) |
| Cape Girardeau to Alpine (California) | 1,562.91 mi (2,515.26 km) |
| Cape Girardeau to Alpine (Utah) | 1,210.95 mi (1,948.84 km) |
| Cape Girardeau to Alsip (Illinois) | 316.46 mi (509.30 km) |
| Cape Girardeau to Altadena (California) | 1,610.49 mi (2,591.84 km) |
| Cape Girardeau to Altamont (Oregon) | 1,730.88 mi (2,785.58 km) |
| Cape Girardeau to Altamonte Springs (Florida) | 761.55 mi (1,225.60 km) |
| Cape Girardeau to Alton (Illinois) | 114.67 mi (184.54 km) |
| Cape Girardeau to Alton (Texas) | 917.67 mi (1,476.85 km) |
| Cape Girardeau to Altoona (Iowa) | 365.26 mi (587.82 km) |
| Cape Girardeau to Altoona (Pennsylvania) | 638.77 mi (1,027.99 km) |
