| Cape Girardeau to Ashtabula (Ohio) | 562.80 mi (905.74 km) |
| Cape Girardeau to Ashwaubenon (Wisconsin) | 501.21 mi (806.61 km) |
| Cape Girardeau to Aspen Hill (Maryland) | 687.97 mi (1,107.18 km) |
| Cape Girardeau to Astoria (Oregon) | 1,851.89 mi (2,980.33 km) |
| Cape Girardeau to Atascadero (California) | 1,727.88 mi (2,780.75 km) |
| Cape Girardeau to Atascocita (Texas) | 601.20 mi (967.53 km) |
| Cape Girardeau to Atchison (Kansas) | 339.47 mi (546.33 km) |
| Cape Girardeau to Athens (Alabama) | 227.41 mi (365.98 km) |
| Cape Girardeau to Athens (Georgia) | 417.90 mi (672.55 km) |
| Cape Girardeau to Athens (Ohio) | 427.61 mi (688.17 km) |
| Cape Girardeau to Athens (Tennessee) | 303.87 mi (489.04 km) |
| Cape Girardeau to Athens (Texas) | 501.03 mi (806.32 km) |
| Cape Girardeau to Atlanta (Georgia) | 378.75 mi (609.54 km) |
| Cape Girardeau to Atlantic Beach (Florida) | 670.88 mi (1,079.67 km) |
| Cape Girardeau to Atlantic City (New Jersey) | 829.99 mi (1,335.74 km) |
