| Cape Girardeau to Beacon (New York) | 879.95 mi (1,416.14 km) |
| Cape Girardeau to Bear (Delaware) | 766.75 mi (1,233.96 km) |
| Cape Girardeau to Beatrice (Nebraska) | 437.58 mi (704.22 km) |
| Cape Girardeau to Beaufort (South Carolina) | 602.19 mi (969.13 km) |
| Cape Girardeau to Beaumont (California) | 1,552.38 mi (2,498.31 km) |
| Cape Girardeau to Beaumont (Texas) | 564.38 mi (908.28 km) |
| Cape Girardeau to Beaver Dam (Wisconsin) | 427.19 mi (687.50 km) |
| Cape Girardeau to Beavercreek (Ohio) | 340.89 mi (548.61 km) |
| Cape Girardeau to Beaverton (Oregon) | 1,798.91 mi (2,895.07 km) |
| Cape Girardeau to Beckley (West Virginia) | 459.83 mi (740.03 km) |
| Cape Girardeau to Bedford (Indiana) | 198.32 mi (319.16 km) |
| Cape Girardeau to Bedford (Ohio) | 512.76 mi (825.21 km) |
| Cape Girardeau to Bedford (Texas) | 527.54 mi (849.00 km) |
| Cape Girardeau to Bedford Heights (Ohio) | 514.56 mi (828.11 km) |
| Cape Girardeau to Beech Grove (Indiana) | 250.67 mi (403.41 km) |
