| Cape Girardeau to Carlsbad (New Mexico) | 897.48 mi (1,444.35 km) |
| Cape Girardeau to Carmel (Indiana) | 259.90 mi (418.27 km) |
| Cape Girardeau to Carmichael (California) | 1,724.02 mi (2,774.54 km) |
| Cape Girardeau to Carney (Maryland) | 720.27 mi (1,159.17 km) |
| Cape Girardeau to Carnot-Moon (Pennsylvania) | 548.58 mi (882.85 km) |
| Cape Girardeau to Carol Stream (Illinois) | 327.27 mi (526.69 km) |
| Cape Girardeau to Carolina (Puerto Rico) | 1,933.85 mi (3,112.23 km) |
| Cape Girardeau to Carolina Forest (South Carolina) | 646.29 mi (1,040.11 km) |
| Cape Girardeau to Carpentersville (Illinois) | 339.23 mi (545.95 km) |
| Cape Girardeau to Carpinteria (California) | 1,682.32 mi (2,707.44 km) |
| Cape Girardeau to Carrboro (North Carolina) | 588.24 mi (946.68 km) |
| Cape Girardeau to Carroll (Iowa) | 433.02 mi (696.88 km) |
| Cape Girardeau to Carrollton (Georgia) | 360.27 mi (579.79 km) |
| Cape Girardeau to Carrollton (Texas) | 510.73 mi (821.94 km) |
| Cape Girardeau to Carrollwood (Florida) | 758.75 mi (1,221.10 km) |
