| Cape Girardeau to Centralia (Illinois) | 87.02 mi (140.05 km) |
| Cape Girardeau to Centralia (Washington) | 1,817.58 mi (2,925.10 km) |
| Cape Girardeau to Centreville (Virginia) | 667.14 mi (1,073.66 km) |
| Cape Girardeau to Ceres (California) | 1,714.41 mi (2,759.07 km) |
| Cape Girardeau to Cerritos (California) | 1,613.18 mi (2,596.16 km) |
| Cape Girardeau to Chalco (Nebraska) | 441.73 mi (710.90 km) |
| Cape Girardeau to Chalmette (Louisiana) | 509.55 mi (820.04 km) |
| Cape Girardeau to Chambersburg (Pennsylvania) | 667.04 mi (1,073.49 km) |
| Cape Girardeau to Chamblee (Georgia) | 378.50 mi (609.14 km) |
| Cape Girardeau to Champaign (Illinois) | 205.72 mi (331.07 km) |
| Cape Girardeau to Champlin (Minnesota) | 578.16 mi (930.46 km) |
| Cape Girardeau to Chandler (Arizona) | 1,284.27 mi (2,066.84 km) |
| Cape Girardeau to Chanhassen (Minnesota) | 561.16 mi (903.11 km) |
| Cape Girardeau to Channahon (Illinois) | 292.33 mi (470.47 km) |
| Cape Girardeau to Channelview (Texas) | 609.81 mi (981.39 km) |
