| Cape Girardeau to Coldwater (Michigan) | 401.72 mi (646.51 km) |
| Cape Girardeau to Colesville (Maryland) | 692.17 mi (1,113.94 km) |
| Cape Girardeau to College (Alaska) | 2,999.39 mi (4,827.05 km) |
| Cape Girardeau to College Park (Georgia) | 382.86 mi (616.16 km) |
| Cape Girardeau to College Park (Maryland) | 695.21 mi (1,118.84 km) |
| Cape Girardeau to College Station (Texas) | 603.78 mi (971.70 km) |
| Cape Girardeau to Collegedale (Tennessee) | 295.97 mi (476.32 km) |
| Cape Girardeau to Colleyville (Texas) | 526.27 mi (846.95 km) |
| Cape Girardeau to Collierville (Tennessee) | 156.61 mi (252.04 km) |
| Cape Girardeau to Collinsville (Illinois) | 97.47 mi (156.86 km) |
| Cape Girardeau to Colonia (New Jersey) | 848.70 mi (1,365.85 km) |
| Cape Girardeau to Colonial Heights (Virginia) | 668.14 mi (1,075.27 km) |
| Cape Girardeau to Colonial Park (Pennsylvania) | 716.26 mi (1,152.71 km) |
| Cape Girardeau to Colorado Springs (Colorado) | 832.60 mi (1,339.93 km) |
| Cape Girardeau to Colton (California) | 1,568.70 mi (2,524.57 km) |
