| Cape Girardeau to Commerce City (Colorado) | 842.92 mi (1,356.55 km) |
| Cape Girardeau to Compton (California) | 1,621.40 mi (2,609.40 km) |
| Cape Girardeau to Comstock Park (Michigan) | 445.85 mi (717.52 km) |
| Cape Girardeau to Concord (California) | 1,766.49 mi (2,842.89 km) |
| Cape Girardeau to Concord (Missouri) | 93.67 mi (150.75 km) |
| Cape Girardeau to Concord (New Hampshire) | 1,030.60 mi (1,658.59 km) |
| Cape Girardeau to Concord (North Carolina) | 513.67 mi (826.67 km) |
| Cape Girardeau to Conneaut (Ohio) | 574.61 mi (924.74 km) |
| Cape Girardeau to Connersville (Indiana) | 288.76 mi (464.71 km) |
| Cape Girardeau to Conroe (Texas) | 590.15 mi (949.76 km) |
| Cape Girardeau to Converse (Texas) | 737.65 mi (1,187.13 km) |
| Cape Girardeau to Conway (Arkansas) | 223.98 mi (360.47 km) |
| Cape Girardeau to Conway (Florida) | 773.03 mi (1,244.06 km) |
| Cape Girardeau to Conway (South Carolina) | 637.33 mi (1,025.68 km) |
| Cape Girardeau to Conyers (Georgia) | 401.64 mi (646.37 km) |
