| Cape Girardeau to Culpeper (Virginia) | 634.95 mi (1,021.86 km) |
| Cape Girardeau to Culver City (California) | 1,628.50 mi (2,620.81 km) |
| Cape Girardeau to Cumberland (Maryland) | 605.74 mi (974.85 km) |
| Cape Girardeau to Cupertino (California) | 1,776.26 mi (2,858.61 km) |
| Cape Girardeau to Cutler Bay (Florida) | 975.00 mi (1,569.11 km) |
| Cape Girardeau to Cutlerville (Michigan) | 433.67 mi (697.92 km) |
| Cape Girardeau to Cuyahoga Falls (Ohio) | 505.59 mi (813.67 km) |
| Cape Girardeau to Cypress (California) | 1,612.54 mi (2,595.13 km) |
| Cape Girardeau to Cypress Gardens (Florida) | 788.80 mi (1,269.46 km) |
| Cape Girardeau to Cypress Lake (Florida) | 868.51 mi (1,397.73 km) |
| Cape Girardeau to D'Iberville (Mississippi) | 474.10 mi (762.99 km) |
| Cape Girardeau to Dakota Ridge (Colorado) | 856.39 mi (1,378.22 km) |
| Cape Girardeau to Dale City (Virginia) | 671.05 mi (1,079.95 km) |
| Cape Girardeau to Dallas (Georgia) | 353.86 mi (569.48 km) |
| Cape Girardeau to Dallas (Oregon) | 1,819.17 mi (2,927.67 km) |
